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Our client is seeking an organic chemist to join their Process Chemistry group. This contract position resides within the Pharmaceutical Sciences organization. The candidate will work full-time onsite and execute laboratory activities related to the development of robust drug substance manufacturing processes across various phases of drug substance development. The ideal candidate will conduct multi-step organic synthesis, route scouting and optimization, purification and characterization of intermediates and final compounds to support drug substance scale-up activities.
An ideal candidate will have a strong foundation in modern synthetic organic chemistry and analytical techniques such as NMR, LCMS, UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments. Experience in small-molecule process development and scale up is highly desired, however not required.
Responsibilities
- Participate in the design, planning and execution of multi-step synthesis, process research and development as a cross-functional team member.
- Collaborate with cross-functional teams to ensure successful project outcomes.
- Implement process enhancements, scientific approaches and technical improvements to deliver robust chemical processes.
- Document and report experimental results and findings.
- Draft and review technical documents (development reports, patent applications, tech transfer documents etc.) Maintain an accurate, timely and compliant laboratory notebook.
- Maintain laboratory equipment and ensure compliance with safety regulations.
Requirements
- An ideal candidate would have a B.S. or M.S. in Chemistry, or a related field with 3+ years of experience in pharmaceutical research or laboratory setting or, Ph.D. with 0-3+ years of experience.
- Strong knowledge of organic chemistry.
- Experience with early phase route development and process optimization Proficiency in using analytical instruments (HPLC/UPLC, NMR, LCMS) and software.
- Strong analytical and problem-solving skills.
- Strong written and verbal communication skills.
- Ability to work independently and as part of a team.
- Strong organizational and time management skills.
- Ability to effectively prioritize and manage multiple tasks and compounds Ability to adapt to change and to work optimally within a variety of situations Ability to build productive working relationships across functions and highly diverse groups of individuals Self-motivated and willing to “learn on the job” and ask for assistance when needed Ability to make a significant impact in a results-driven environment where accountability is key.
- A team player, who listens effectively and invites response and discussion A collaborator who communicates in an open, transparent, complete, timely and consistent manner
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